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The Ability of a Removed Liver to Regrow Lies In the Blood, Scientists Explain How

Fibrinogen and blood platelets help the liver to regenerate after surgical removal.

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fibrinogen and platelets for liver regeneration
Fibrinogen and platelets are essential for liver regeneration. Photo Credit: Frolicsomepl/Pixabay
Press Release

Scientists say the liver is the only organ in the body that can regrow itself after removal. They further revealed the ability of the liver to regenerate itself lies in the blood. With the activity of the blood-clotting protein, fibrinogen, the liver is able to regrow again if a portion of it is removed via surgery. But this may not always happen. And scientists now understand why.

In a study published in the journal Blood, researchers from the Michigan State University present their findings.

According to their findings, the researchers said fibrinogen holds the secret to liver regeneration. Fibrinogen is a protein present in blood plasma; it converts to fibrin when blood clots. Where a liver fails to regenerate following a resection, the fibrinogen is also to blame.

Fibrinogen and Platelets Are Crucial To Liver Regeneration or Dysfunction Following Surgery

James Luyendyk, a professor of pathobiology in the College of Veterinary Medicine of the Michigan State University explained this phenomenon in details. According to Luyendyk, fibrinogen sets up a network of activity where a section of the liver is removed. Fibrinogen activates platelets to rush to the site of removal, building a chemical activity that triggers organ regeneration at the point of liver resection.

In a case where blood platelets or fibrinogen are inhibited from reaching, the resected liver finds it difficult to heal or regenerate itself.

fibrinogen and platelets for liver regeneration 1

Fibrinogen and platelets are essential for liver regeneration. Photo Credit: Qimono/Pixabay

Platelets are blood cells that enable clots to form at the site of a fresh wound, effectively stopping bleeding. As soon as a portion of a damaged liver is removed, fibrinogen sends instant information to platelets which rush off to the site to initiate repairs.

The intervention of fibrinogen and instant action of platelets increase the ability of a damaged or repaired liver to heal and regrow itself into full functionality again. But in a situation where insufficient fibrinogen activity is recorded, the number of platelets drawn to a resected liver becomes significantly low – impacting the recovery process.

Comprehending How Fibrinogen Works In Mice Will Help Liver Patients Access Treatments

The team of researchers said doctors would do well to measure fibrinogen levels in patients who have had a portion of their liver removed. This will enable them to determine if the liver will be able to regenerate itself easily or if it will remain dysfunctional.

“This shows that fibrinogen deposits are extremely important and directly impact regeneration in both mice and humans,” Luyendyk said.

With this advance knowledge, medical researchers can develop new treatments for correcting low fibrinogen levels. A potential option might be developing fibrinogen concentrates that can be administered at the point of a resected liver during surgery.

Luyendyk said this treatment potential had never been tried in liver resection patients before. He added that when scientists fully comprehend how fibrinogen functions for organ regeneration in mice models, they will be able to conduct trials in liver patients with a view to helping them regrow their liver after surgical removal.

This post was originally published on Health News Office

Amanda graduated from the University of Michigan where she studied Business and Communication. She owns her own internet business but loves to write health articles in her spare time. Based in California, she is married with two lovely boys.

Health Studies

Cleanroom Lighting Market to Showcase Stringent Growth during 2019-2024

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The analysts forecast the global cleanroom lighting market to exhibit a CAGR of 5.58% during the period 2019-2024. The report covers the present scenario and the growth prospects of the global cleanroom lighting for 2019-2024. To calculate the market size, the report considers the cleanroom lighting sales volume and revenue.

Request for Sample Report @ https://www.factomarketinsights.com/sample/102

The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: regional markets, product, and application.

Geographically, the global cleanroom lighting market is segmented into North America, Asia Pacific, Europe, Middle East & Africa and South America. This report forecasts revenue growth at a global, regional & country level, and provides an analysis of the market trends in each of the sub-segments from 2019 to 2024.

– North America (U.S., Canada, Mexico, etc.)
– Asia-Pacific (China, Japan, India, Korea, Australia, Indonesia, Taiwan, Thailand, etc.)
– Europe (Germany, UK, France, Italy, Russia, Spain, etc.)
– Middle East & Africa (Turkey, Saudi Arabia, Iran, Egypt, Nigeria, UAE, Israel, South Africa, etc.)
– South America (Brazil, Argentina, Colombia, Chile, Venezuela, Peru, etc.)

On the basis of product, the global cleanroom lighting market is segmented into:

– LED Cleanroom Lighting
– Fluorescent Cleanroom Lighting

Based on application, the cleanroom lighting market is segmented into:

– Healthcare & Life Science
– Industrial Manufacturing
– Food & Beverage

The report also includes a discussion of the key vendors operating in this market. Some of the leading players in the global cleanroom lighting market are:

– Cleanroom Industries Sdn. Bhd.
– Crompton Greaves Ltd.
– Eaton Corporation plc
– Legrand SA (Kenall Manufacturing Company, Inc.)
– Linder AG
– Ludwig Leuchten GmbH & Co. KG
– LUG Light Factory Sp. z o.o.
– Signify Holding BV
– Solite Europe Ltd.
– Wipro Enterprises (P) Ltd.
– request free sample to get a complete list of companies

Request for Research Methodology @ https://www.factomarketinsights.com/method/102

Objective of the study:

– To analyze and forecast the market size of global cleanroom lighting market.
– To classify and forecast global cleanroom lighting market based on region, product, and application.
– To identify drivers and challenges for global cleanroom lighting market.
– To examine competitive developments such as expansions, mergers & acquisitions, etc., in global cleanroom lighting market.
– To conduct pricing analysis for global cleanroom lighting market.
– To identify and analyze the profile of leading players operating in global cleanroom lighting market.

The report is useful in providing answers to several critical questions that are important for the industry stakeholders such as manufacturers and partners, end users, etc., besides allowing them in strategizing investments and capitalizing on market opportunities. Key target audience are:

– Manufacturers of cleanroom lighting
– Raw material suppliers
– Market research and consulting firms
– Government bodies such as regulating authorities and policy makers
– Organizations, forums and alliances related to cleanroom lighting

Get Report Sample Copy @ https://www.factomarketinsights.com/sample/102

The information contained in this report is based upon both primary and secondary sources. Primary research included interviews with cleanroom lighting suppliers and industry experts. Secondary research included an exhaustive search of relevant publications like company annual reports, financial reports, and proprietary databases.

About Us

Facto market insights is one of the leading providers of market intelligence products and services. We offer reports on over 10+ industries and update our collection daily which helps our clients to access database of expert market insights on global industries, companies, products, and trends.

Our in-house research experts have a wealth of knowledge in their respective domains. With Facto Market Research, you always have the choice of getting customized report free of cost (upto 10%). Our support team will help you customize the report and scope as per your business needs. This ensures that you are making the right purchase decision.

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This post was originally published on Health News Office

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Health Studies

Varicose Vein Treatment Market Sparkling Growth Worldwide Forecast by 2025

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Press Release

The global varicose vein treatment market was valued at $376.64 million in 2017, and is expected to reach $589.06 million by 2025, registering a CAGR of 5.7% from 2018 to 2025. Varicose veins are abnormal, dilated blood vessels caused by weakening of the vessel’s walls. These veins appear to be swollen, twisted, cluster of blue or purple veins under the skin. Varicose vein disorder affects millions of people all around the world Symptoms usually appear at the age of 40 and generally appear in the legs. Varicose vein is harmful to health if they lead to venous stasis ulcers, phlebitis, thrombosis, venous hemorrhage, or fungal and bacterial infections. According to the American Society of Vascular surgery, at least 20 to 25 million Americans are suffering from varicose vein, among them 17% are men and 33% are women.

Get Report Sample Copy for Detailed Insights @ https://www.factomarketinsights.com/sample/299

Considerable rise in prevalence of varicose vein problem, surge in geriatric population, advanced varicose vein treatment devices, engagement in occupation that increases the prevalence of varicose vein treatment and technological advancements globally, boost the growth of the market. Whereas, increase in level of awareness as well as development in the emerging markets create numerous opportunities in the varicose vein treatment market.

The global varicose vein treatment market is segmented based on procedure, product, end user, and region. Based on procedure, the market is endovenous ablation, injection sclerotherapy, surgical ligation/stripping. Based on product the market is segmented into ablation devices, sclerotherapy injection and others. Ablation devices is further divided into radiofrequency ablation devices, laser ablation devices and others. Based on end user, the market is divided into hospital, clinics, and ambulatory centers. Based on region, the market is studied across North America (U.S., Canada, and Mexico), Europe (Germany, France, the UK, Italy, Spain and rest of Europe), Asia-Pacific (China, Japan, Australia, India, South Korea and rest of Asia-Pacific) and LAMEA (Brazil, South Africa, Saudi Arabia, and rest of LAMEA).

Key Benefits for varicose vein treatment market:

The study presents an in-depth analysis of the market along with the current trends and future estimations to elucidate the imminent investment pockets.
It offers a quantitative analysis from 2018 to 2025, which is expected to enable the stakeholders to capitalize on the prevailing market opportunities.
A comprehensive analysis of all the regions is provided to determine the existing opportunities.

The profiles and growth strategies of the key players are thoroughly analyzed to understand the competitive outlook of the global market.

Request for Research Methodology @ https://www.factomarketinsights.com/method/299

Varicose vein treatment Key Market Segments:

By Procedure

Injection Sclerotherapy
Endovenous Ablation
Surgical Ligation/Stripping

By Product

Sclerotherapy injection
Ablation Devices
Radiofrequency Ablation Devices
Laser Ablation Devices
Others
Others

By End User

Hospitals
Clinics
Ambulatory centers

By Region

North America
U.S.
Canada
Mexico
Europe
Germany
France
UK
Italy
Spain
Rest of Europe
Asia-Pacific
Japan
China
Australia
India
South Korea
Rest of Asia-Pacific
LAMEA
Brazil
Saudi Arabia
South Africa
Rest of LAMEA

Send an Enquiry @ https://www.factomarketinsights.com/enquiry/299

LIST OF KEY PLAYERS PROFILED IN THE REPORT

Alma Lasers Ltd
Angiodynamics, Inc
Biolitec AG
BTG PLC
Energist Ltd
Medtronic
Lumenis
Sciton Inc
Syneron
WONTECH Co., Ltd.

 About Us

Facto market insights is one of the leading providers of market intelligence products and services. We offer reports on over 10+ industries and update our collection daily which helps our clients to access database of expert market insights on global industries, companies, products, and trends.

Our in-house research experts have a wealth of knowledge in their respective domains. With Facto Market Research, you always have the choice of getting customized report free of cost (upto 10%). Our support team will help you customize the report and scope as per your business needs. This ensures that you are making the right purchase decision.

Contact Us

United States

150 State St.
Suite 301
Albany, NY 12207
United States
Email: [email protected]

Tel: +1 518-300-1215

This post was originally published on Health News Office

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Health Studies

Europe Early Toxicity Testing Market Trends, Opportunities & Revenue Share Analyzed during 2018-2025

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The Europe early toxicity testing market accounted for $265 million in 2017, and is expected to reach $460 million by 2025, registering a CAGR of 7.1% from 2018 to 2025.

Toxicity is the degree of threat posed by a substance to the living organism, and toxicology is a branch of science that deals with measurement and further analysis of these chemical substances and their adverse effects on the body of an organism. The effects of chemical substances on the body are studied to choose a potential drug candidate during the development of newer molecules. Early toxicity testing is carried out at preclinical stages of a drug development process and is essential as toxicity serves as the major reason for the failure of potential drug candidates in the later stages of drug development leading to huge financial loss to companies. Moreover, companies perform early toxicity testing to comply with the government standards to market the drug. Early toxicity testing can be performed using different techniques such as in vivo, in vitro, and in silico. These techniques are employed to carry out different toxicity tests such as ocular toxicity, carcinogenicity, systemic toxicity, and others.

Get Report Sample Copy for Detailed Insights @ https://www.factomarketinsights.com/sample/291

Major factors that drive the market growth are surge in the research and development activities and increase in stringency of regulatory authorities concerning public healthcare welfare. In addition, technological advancements in vitro techniques, rise in adoption of in vitro models in the Europe early toxicity testing industry and surge in adoption of early toxicity testing further boost the market growth. However, limitations associated with preclinical testing hamper the market growth. Furthermore, the technological advancements related to early toxicity testing provide lucrative opportunities for the market growth during the forecast period.

This report segments the Europe early toxicity testing market on the basis of technique, application, end users, and country to provide a detailed assessment of the market. Based on technique, the market is divided into in vivo, in vitro, and in silico. The market on the basis of in vitro is further divided into in vitro toxicity testing market by assays and in vitro toxicity testing market by toxicity endpoints. The in vitro toxicity testing market by assays is further segmented into enzyme toxicity assays, bacterial toxicity assays, cell-based ELISA & western blots, receptor binding assays, and other assays. The in vitro toxicity testing market by toxicity endpoints is further divided into dermal toxicity, systemic toxicity, carcinogenicity, ocular toxicity, skin sensitization and irritation, neurotoxicity, organ toxicity, and other toxicity endpoints. Based on country, the market is studied across different countries of Europe such as Germany, France, the UK, and rest of Europe.

KEY BENEFITS FOR STAKEHOLDERS

ü The study provides an in-depth analysis of the Europe early toxicity testing market along with the current trends and future estimations to elucidate the imminent investment pockets.
ü A quantitative analysis from 2017 to 2025 is discussed to enable the stakeholders to capitalize on the prevailing market opportunities.
ü In-depth analysis of early toxicity testing techniques such as in vivo, in vitro, and in silico is carried out in the report.
ü The profiles and growth strategies of the key players are thoroughly analyzed to understand the competitive outlook of the European market.

Outlook Complete Research Report with TOC @ https://www.factomarketinsights.com/report/291/europe-early-toxicity-testing-market-amr

KEY MARKET SEGMENTS

By Technique
o In Vivo
o In Vitro
§ In Vitro Toxicity Testing Market by Assays
• Enzyme Toxicity Assays
• Bacterial Toxicity Assays
• Cell-Based ELISA and Western Blots
• Tissue Culture Assays
• Receptor Binding Assays
• Other Assays
§ In Vitro Toxicity Testing Market by Toxicity Endpoints
• Dermal Toxicity
• Systemic Toxicity
• Carcinogenicity
• Ocular Toxicity
• Skin Sensitization and Irritation
• Genotoxicity
• Neurotoxicity
• Organ Toxicity
• Other Toxicity Endpoints
o In Silico

By Application
o Drug discovery
o Chemical testing
o Others

By End User
o Pharmaceuticals Industry
o Food Industry
o Chemicals Industry
o Cosmetics Industry
o Other Industries

By Country
o Germany
o France
o UK
o Rest of Europe

Request for Research Methodology @ https://www.factomarketinsights.com/method/291

LIST OF KEY PLAYERS PROFILED IN THE REPORT (DEVICE PROVIDERS)

  • Agilent Technologies, Inc.
    • General Electric Company (GE Healthcare)
    • Danaher Corporation (Beckman Coulter, Inc.)
    • Evotec AG (Cyprotex)
    • Bioanalytical Systems, Inc.
    • Bruker Corporation
    • Thermo Fisher Scientific, Inc.
    • PerkinElmer Inc.
    • Enzo Biochem, Inc. (Enzo Clinical Labs, Inc.)
    • The Jackson Laboratory

 About Us

Facto market insights is one of the leading providers of market intelligence products and services. We offer reports on over 10+ industries and update our collection daily which helps our clients to access database of expert market insights on global industries, companies, products, and trends.

Our in-house research experts have a wealth of knowledge in their respective domains. With Facto Market Research, you always have the choice of getting customized report free of cost (upto 10%). Our support team will help you customize the report and scope as per your business needs. This ensures that you are making the right purchase decision.

Contact Us

United States

150 State St.
Suite 301
Albany, NY 12207
United States
Email: [email protected]

Tel: +1 518-300-1215

This post was originally published on Health News Office

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