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Scientists Discover How a Sleeping Cancer Awakens and Metastasizes

Dormant breast & prostate cancer cells that have traveled to the lungs can awaken and metastasize.

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skin cancer cells
Sleeping cancers can awaken and metastasize. Photo Credit: PDPics/Pixabay

A new study reveals that cancers in remission are capable of reawakening again. Researchers from the Cold Spring Harbor Laboratory (CSHL) demonstrated how sleeping cancers awaken and metastasize. Based on this knowledge, they developed a treatment plan that can prevent dormant cancer cells from awakening again.

The research was carried out in lab mice with hopes of being tested on humans soon.

According to the researchers, a patient successfully treated and cured of cancer can still become afflicted with the disease again. This is largely because dormant, non-dividing cancer cells that previously detached from an original tumor may move elsewhere to exist in other parts of the body. Once awakened, these dormant cancer cells can multiply and develop into metastatic tumors.

Cancers Become Most Fatal When They Spread Fast To Other Parts of the Body

Metastasis is the spreading of cancer disease from one part of the body to others.

The CSHL team together with scientists from the Dana Farber Cancer Institute and University of California, Davis, found triggers that could reawaken dormant cancer cells. They discovered this while studying metastasis to the lungs.

They found that inflammation of the lungs – caused by tobacco smoking and other factors – can make passive breast and prostate cancer cells which had earlier moved to the lungs to wake up and begin to multiply. The now active cells can grow all over the lungs.

Most common cancers become highly lethal when they metastasize or spread to become active in other parts of the body.

The scientists were however able to block the signals that awakened the dormant cancer cells, demonstrating that cancer progression could be arrested or reversed.

Led by CSHL Associate Professor Mikala Egeblad, the team found that neutrophils awaken surrounding passive cancer cells with lung inflammation caused by tobacco smoke or endotoxin. Neutrophils are common white blood cells, and endotoxin is a bacteria component.

With Successful Trials in Lab Mice, Cured Cancer May Remain in Soon Remain in Remission

Neutrophils destroy bacteria and yeast among other pathogens that invade our bodies. One of the ways they do this is to push out the DNA of the invaders outside of their cell membranes. Armed with toxic enzymes, the expelled DNA creates net-like traps to vanquish pathogens. The net-like trap is known as neutrophil extracellular traps or NETs.

NETs form around dormant cancer cells of patients having prolonged lung inflammation. NETs contains two enzymes known as neutrophil elastase (NE) and matrix metalloproteinase 9 (MMP9). Both NE and MMP9 interact with laminin, a tissue containing protein. NE goes ahead to cut into laminin proteins and MMP9 also does the same. This changes the protein’s shape, exposing a new surface, called an epitope.

When passive cancer cells sense the presence of epitope nearby, they are triggered to begin reawakening and then multiplying. As soon as dormant cancer cells recognize new shapes in the laminin, they are roused from sleep and begin to metastasize.

To prevent dormant cancer cells from rousing, the research team created an antibody that blocks the epitome exposed on the laminin proteins. The scientists have also begun to optimize the antibody to interfere with the activity of NETs, effectively keeping cancer in remission in rats. The researchers hope to begin conducting trials of this study on people soon.

Liu Kang is an American with Chinese ancestry. She attended University of Maryland where she studied Political Science. She worked on the politics desks of newspapers and later switched to the health desk where she covered health issues. She is married with two kids. She records personal songs in her spare time.

Diseases & Disorders

Biobanking Market Industry Analysis, Size, Share, Growth, Key Trends and Forecast To 2023

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Biobanking Market

The study methodologies used to examine the Biobanking Market  for the forecast period, 2019 – 2023 further classifies the industry by type, geography, end-use and end-user to add more precision and bring to light factors responsible for augmenting business development.

Request For FREE Sample Copy of this report to get the details of Top Companies, Types And Application @ https://www.marketgrowthinsight.com/sample/47725

Scope of the Report:

The researcher assessing the Biobanking Market  dive deep to unearth intangible facts related to the key restraints, opportunities, and threats expected to shape the progress of the industry during the forecast period, 2019 – 2023. Significant evaluation of other factors such as demand and supply status, import and export, distribution channel, consumption volume, and production capability play a vital role in offering business owners, stakeholders and field marketing personnel a competitive edge over others operating in the same space. All important data are presented in self-explanatory charts, tables and graphic images that can be incorporated into any business presentation.

The latest research, Biobanking Market  allows companies and individuals learn more about the yesteryears, present and potential buyers in the Biobanking Market  for the forecast period, 2019 – 2023 .Most importantly, the study enables business owners to understand and make better business decisions by pinpointing the current demands and needs of the consumers. The collection of data with an aim to offer clarity on consumer behaviour in a particular region where the Biobanking Market  players operate makes the report more valuable. Apart from this, the study evaluates the competitors in a specific country. Another critical aspect that is covered by this literature on Biobanking Market  is the effective assessment of small marketing campaigns.

The research further holds ample information to enable stakeholders in their decision-making process, especially associated with problem identification, finding the best solutions as well as opportunities in the Biobanking Market  for the forecast period, 2019 – 2023. The study further document marketing benchmarks that a business owner is expected to complete in order to sustain in the highly saturated market. Besides, the marketing efforts and constant improvements introduced to the marketing strategy by major vendors’ forms an important part of the study.

The report helps product manufacturers connect directly to their target audience by including thoughts and opinions from companies and individuals who are unbiased and less emotionally attached to recent developments, products or services. The study empowers field marketing executives to gain a new angle on how they should go about a new launch, a new product or brand positioning. As a part of their exercise, the researchers have not only provided the sales estimation of the products and services but have also documented the winning strategies required to achieve and maximize the profits.

Buy Biobanking Market  Reporthttps://www.marketgrowthinsight.com/checkout/47725

The study explores in details about the recent trend fast gaining momentum in the Biobanking Market  industry due to factors including but not limited to growing customer preference and a sudden rise in their spending capacity. Aspects attributed to the gross margin, profit, supply chain management and product value and their considerable impact on the development of the Biobanking Market  during the forecast period, 2019 – 2023 is carefully scrutinized during the research.

Estimating the potential size of the Biobanking Market  industry:
Industry experts conducting the study further estimate the potential of the Biobanking Market  industry. Such information is important for firms looking to launch an innovative service or product on the market. Industry experts have measured the total volume of the given market. Researchers have calculated the industry in terms of sales by the competitors and end-user – customers. Data on the entire size of the Biobanking Market  for a particular product or a service for the forecast period, 2019 to 2023 covered in the report makes it valuable. This information reveals the upper limit of the Biobanking Market  industry for a specific product or service.

Exploring growth rate over a period:
Business owners looking to scale up their business can refer this report that contains data regarding the rise in sales within a given consumer base for the forecast period, 2019 to 2024. Product owners can use this information along with the driving factors such as demographics and revenue generated from other products discussed in the report to get a better analysis of their products and services. Besides, the research analysts have compared the market growth rate with the product sales to enable business owners to determine the success or failure of a specific product or service.

Read More @ https://www.marketgrowthinsight.com/47725/biobanking-market-research

The research provides answers to the following key questions:
– What is the estimated size of the Biobanking Market  for the forecast period, 2019 – 2023? What will be the growth rate of the industry during the estimated period?
– What are the prominent driving forces likely to impact the progress of the industry across different regions?
– Who are the major market players occupying a strong foothold in the Biobanking Market  ? What are the winning strategies adopted by them to stay ahead in the competition?
– What are the potential opportunities for the Biobanking Market  for the forecast period, 2019 – 2023?

People also viewed:

Feed Mycotoxin Binders & Modifiers Market Insights Report 2019 | Global Trends, Opportunities, Analysis and Forecast by 2026 @ https://www.marketgrowthinsight.com/sample/43405

 

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Market Growth Insight is a one stop solution for market research reports in various business categories. We are serving 100+ clients with 10000+ diverse industry reports and our reports are developed to simplify strategic decision making, on the basis of comprehensive and in-depth significant information, established through wide ranging analysis and latest industry trends.

We are striving to provide the best customer friendly services and appropriate business information to accomplish your ideas.

 

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Diseases & Disorders

Ready To Use 1-Chlorooctane Market Growth and Forecast 2019-2020

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In 2018, the market size of 1-Chlorooctane Market is million US$ and it will reach million US$ in 2025, growing at a CAGR of from 2018; while in China, the market size is valued at xx million US$ and will increase to xx million US$ in 2025, with a CAGR of xx% during forecast period.

In this report, 2018 has been considered as the base year and 2018 to 2025 as the forecast period to estimate the market size for 1-Chlorooctane .

This report studies the global market size of 1-Chlorooctane , especially focuses on the key regions like United States, European Union, China, and other regions (Japan, Korea, India and Southeast Asia).

Request Sample Report @ https://www.marketresearchhub.com/enquiry.php?type=S&repid=2486260&source=atm

This study presents the 1-Chlorooctane Market production, revenue, market share and growth rate for each key company, and also covers the breakdown data (production, consumption, revenue and market share) by regions, type and applications. 1-Chlorooctane history breakdown data from 2014 to 2018, and forecast to 2025.

For top companies in United States, European Union and China, this report investigates and analyzes the production, value, price, market share and growth rate for the top manufacturers, key data from 2014 to 2018.

In global 1-Chlorooctane market, the following companies are covered:

Jingmen Meifeng Chemical
Yancheng Yunfeng Chemical
Jiande Xingfeng Chemical
Shijiazhuang Sincere Chemicals
Yancheng Longsheng Chemical
Yancheng Jinbiao Chemical
Jingmen Hefeng Technology

1-Chlorooctane Breakdown Data by Type
Purity 98%
Purity 99%

1-Chlorooctane Breakdown Data by Application
Surface Active Agent
Pharmaceutical Ingredient
Stabilizer
Chemical Intermediate

1-Chlorooctane Production Breakdown Data by Region
North America
Europe
China
Japan

1-Chlorooctane Consumption Breakdown Data by Region
North America
United States
Canada
Mexico
Europe
Germany
France
UK
Italy
Russia
Asia-Pacific
China
Japan
South Korea
India
Australia
Indonesia
Thailand
Malaysia
Philippines
Vietnam
Central & South America
Brazil
Middle East & Africa
Turkey
GCC Countries
Egypt
South Africa

Make An Enquiry About This Report @ https://www.marketresearchhub.com/enquiry.php?type=E&repid=2486260&source=atm 

The content of the study subjects, includes a total of 15 chapters:

Chapter 1, to describe 1-Chlorooctane product scope, market overview, market opportunities, market driving force and market risks.

Chapter 2, to profile the top manufacturers of 1-Chlorooctane , with price, sales, revenue and global market share of 1-Chlorooctane in 2017 and 2018.

Chapter 3, the 1-Chlorooctane competitive situation, sales, revenue and global market share of top manufacturers are analyzed emphatically by landscape contrast.

Chapter 4, the 1-Chlorooctane breakdown data are shown at the regional level, to show the sales, revenue and growth by regions, from 2014 to 2018.

Chapter 5, 6, 7, 8 and 9, to break the sales data at the country level, with sales, revenue and market share for key countries in the world, from 2014 to 2018.

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Chapter 10 and 11, to segment the sales by type and application, with sales market share and growth rate by type, application, from 2014 to 2018.

Chapter 12, 1-Chlorooctane market forecast, by regions, type and application, with sales and revenue, from 2018 to 2024.

Chapter 13, 14 and 15, to describe 1-Chlorooctane sales channel, distributors, customers, research findings and conclusion, appendix and data source.

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Diseases & Disorders

Mycotoxin Testing Market Industry Analysis, Size, Share, Growth, Key Trends and Forecast To 2023

Published

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Mycotoxin Testing Market

The study methodologies used to examine the Mycotoxin Testing Market  for the forecast period, 2019 – 2023 further classifies the industry by type, geography, end-use and end-user to add more precision and bring to light factors responsible for augmenting business development.

Request For FREE Sample Copy of this report to get the details of Top Companies, Types And Application @ https://www.marketgrowthinsight.com/sample/47716

Scope of the Report:

The researcher assessing the Mycotoxin Testing Market  dive deep to unearth intangible facts related to the key restraints, opportunities, and threats expected to shape the progress of the industry during the forecast period, 2019 – 2023. Significant evaluation of other factors such as demand and supply status, import and export, distribution channel, consumption volume, and production capability play a vital role in offering business owners, stakeholders and field marketing personnel a competitive edge over others operating in the same space. All important data are presented in self-explanatory charts, tables and graphic images that can be incorporated into any business presentation.

The latest research, Mycotoxin Testing Market  allows companies and individuals learn more about the yesteryears, present and potential buyers in the Mycotoxin Testing Market  for the forecast period, 2019 – 2023 .Most importantly, the study enables business owners to understand and make better business decisions by pinpointing the current demands and needs of the consumers. The collection of data with an aim to offer clarity on consumer behaviour in a particular region where the Mycotoxin Testing Market  players operate makes the report more valuable. Apart from this, the study evaluates the competitors in a specific country. Another critical aspect that is covered by this literature on Mycotoxin Testing Market  is the effective assessment of small marketing campaigns.

The research further holds ample information to enable stakeholders in their decision-making process, especially associated with problem identification, finding the best solutions as well as opportunities in the Mycotoxin Testing Market  for the forecast period, 2019 – 2023. The study further document marketing benchmarks that a business owner is expected to complete in order to sustain in the highly saturated market. Besides, the marketing efforts and constant improvements introduced to the marketing strategy by major vendors’ forms an important part of the study.

The report helps product manufacturers connect directly to their target audience by including thoughts and opinions from companies and individuals who are unbiased and less emotionally attached to recent developments, products or services. The study empowers field marketing executives to gain a new angle on how they should go about a new launch, a new product or brand positioning. As a part of their exercise, the researchers have not only provided the sales estimation of the products and services but have also documented the winning strategies required to achieve and maximize the profits.

Buy Mycotoxin Testing Market  Reporthttps://www.marketgrowthinsight.com/checkout/47716

The study explores in details about the recent trend fast gaining momentum in the Mycotoxin Testing Market  industry due to factors including but not limited to growing customer preference and a sudden rise in their spending capacity. Aspects attributed to the gross margin, profit, supply chain management and product value and their considerable impact on the development of the Mycotoxin Testing Market  during the forecast period, 2019 – 2023 is carefully scrutinized during the research.

Estimating the potential size of the Mycotoxin Testing Market  industry:
Industry experts conducting the study further estimate the potential of the Mycotoxin Testing Market  industry. Such information is important for firms looking to launch an innovative service or product on the market. Industry experts have measured the total volume of the given market. Researchers have calculated the industry in terms of sales by the competitors and end-user – customers. Data on the entire size of the Mycotoxin Testing Market  for a particular product or a service for the forecast period, 2019 to 2023 covered in the report makes it valuable. This information reveals the upper limit of the Mycotoxin Testing Market  industry for a specific product or service.

Exploring growth rate over a period:
Business owners looking to scale up their business can refer this report that contains data regarding the rise in sales within a given consumer base for the forecast period, 2019 to 2024. Product owners can use this information along with the driving factors such as demographics and revenue generated from other products discussed in the report to get a better analysis of their products and services. Besides, the research analysts have compared the market growth rate with the product sales to enable business owners to determine the success or failure of a specific product or service.

Read More @ https://www.marketgrowthinsight.com/47716/mycotoxin-testing-market-research

The research provides answers to the following key questions:
– What is the estimated size of the Mycotoxin Testing Market  for the forecast period, 2019 – 2023? What will be the growth rate of the industry during the estimated period?
– What are the prominent driving forces likely to impact the progress of the industry across different regions?
– Who are the major market players occupying a strong foothold in the Mycotoxin Testing Market  ? What are the winning strategies adopted by them to stay ahead in the competition?
– What are the potential opportunities for the Mycotoxin Testing Market  for the forecast period, 2019 – 2023?

People also viewed:

Feed Mycotoxin Binders & Modifiers Market Insights Report 2019 | Global Trends, Opportunities, Analysis and Forecast by 2026 @ https://www.marketgrowthinsight.com/sample/43405

 

About us

Market Growth Insight is a one stop solution for market research reports in various business categories. We are serving 100+ clients with 10000+ diverse industry reports and our reports are developed to simplify strategic decision making, on the basis of comprehensive and in-depth significant information, established through wide ranging analysis and latest industry trends.

We are striving to provide the best customer friendly services and appropriate business information to accomplish your ideas.

Our Media Distributor:- https://www.marketwatch.com/press-release/biodegradable-plastic-bags-and-sacks-market-data-analysis—forecast-2019-2024-2019-10-31

 

Contact

Contact No– :+13477675477(US) / +44 131 463 4161(UK)

[email protected]

Website- https://www.marketgrowthinsight.com

Follow Us:- LinkedIn | Twitter | Google+ | Facebook

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